As part of CIBM’s Teaching Initiative 2022, the newly created CIBM Translational MR Neuroimaging & Spectroscopy PhD course PHYS-760 / 3 crédits took place from April 24th- May 5th, 2023 at EPFL.
The comprehensive course on Magnetic Resonance Imaging (MRI) and Spectroscopy (MRS) was designed for PhD students and Post-docs across the Lemanic region wanting to gain first hand knowledge and practical training conducted by experts in the field and members of the CIBM Community.
EPFL:
CHUV-UNIL:
UNIGE and Siemens Healthineers:
The topics included experimental design, data gathering, and processing in MRS, as well as, structural and functional MRI in both humans and rodents. Upon completion of the course, students are able to understand the physical principles of MRI and MRS, design a translational study, establish MRI and MRS acquisition protocols, and analyze results for their research interests. Additionally, they are be able to perform MRI, MRS, and DWI, as well as perform simple quantification and modelling on provided data. The program provided an opportunity for students to work on hands-on exercises and questions in groups, fostering interdisciplinary interaction and collaboration.
This was a great opportunity to learn and enhance their skills in the field of MRI and MRS.
To find out more, please visit the course link and the booklet is also available for download here.
Program of the course
Monday
8:15- 10:00 Introduction to MRI and MRS (Xin)
10:15 – 11:00 Ethics for human study (Fornari)
11:15 – 12:00 Ethics for animal study (Cudalbu)
13:15-14:00 Basics of nuclear magnetic resonance I (Wenz)
14:15-15:00 Basics of nuclear magnetic resonance II (Lanz)
15:15-16:00 Basics of MRI (Cudalbu)
16:15-17:00 Basic of MR sequences (van Heeswijk)
Tuesday
13:15-14:30 Brain structure & function I : tools for whole-brain connectivity and brain-behavior interactions (Zerbi)
14:45-15:45 MRI sequences and applications of functional imaging (Zerbi)
16:00-17:00 MRI sequences and applications of diffusion-weighted imaging (Jelescu)
Wednesday
Group1
8:15- 9:00 RF theory: introduction & demonstration (Wenz)
10:15 – 12:00 Hands-on: RF coil construction and characterization at the bench (Wenz)
Group 2
13:15- 14:00 RF theory: introduction & demonstration (Wenz)
14:15 – 17:00 Hands-on: RF coil construction and characterization at the bench (Wenz)
Thursday
08:15-09:00 Introduction of MRS I (Xin)
09:15-10:00 Introduction of MRS II (Xin)
10:15-11:00 Basics of MRSI (Cudalbu)
11:15-12:00 Fast MRSI (Klauser)
13:15-17:00, Group 1 7T MRI & MRS demonstration & hands-on
13:15-17:00, Group 2 14T MRI & MRS demonstration & hands-on
Friday
08:15-12:00, Group 2 7T MRI & MRS demonstration & hands-on
08:15-12:00, Group 1 14T MRI & MRS demonstration & hands-on
Monday
8:15- 09:00 X nuclei MRS (13C, 31P, 15N, 2H). (Xin)
09:15 – 10:00 MRS Quantification (Cudalbu)
10:15 – 12:00 Interpretation of dynamic X-nuclei experiments with metabolic modelling (Lanz)
13:15-15:15 1H MRS quantification: demonstration & hands-on (Cudalbu)
15:30-17:00 X-nuclei data modeling: demonstration & hands-on (Lanz)
Tuesday
8:15 – 12:00 Theory of clinical MRI segmentation and registration for MP2RAGE. Introduction to surface and voxel based morphometry (VBM and SBM) and fMRI processing. (Cuadra & Fornari)
13:15 – 17:00 Lab for structure MRI processing (VBM and SBM) and fMRI (Cuadra & Fornari)
Wednesday and Thursday
Free
Friday
8:15-9:00 Brain structure & function II:an introduction to rodent MRI; history, potentials, caveats & hardware (Zerbi)
9:15-10:00 Rodent multimodal fMRI. Tools for manipulating neural activity & fMRI applications (Zerbi)
10:15-12:00 Translational fMRI. Assessing (dys)similarities across species using fMRI and brain connectivity (Zerbi)
Keywords
Magnetic Resonance Imaging (MRI); Magnetic Resonance Spectroscopy (MRS); functional MRI; diffusion MRI; Imaging; MR Hardware; Coil Design;