Visitors Talk : The water signal in 1H-MRS: nuisance or blessing?
Dr. Cristina Cudalbu from the CIBM MRI EPFL AIT section is organizing and inviting you to attend a morning seminar on MR Spectroscopy methods on July 7th at 10 am.
Roland Kreis
Professor University & Inselspital Bern. Magnetic Resonance in Medicine Group (DIN-DBMR)
Prof. Kreis is a researcher from the University of Bern who has dedicated his professional career to in vivo MR spectroscopy, where he has been lucky to be involved in pioneering applications of human brain MRS at HMRI in Pasadena, USA, and later in early work on muscle and liver MRS in Bern. Further, he is most well-known for his methodological work in quantitation, quality control, and processing strategies. Details and a publication record can be found here.
The water signal in 1H-MRS: nuisance or blessing?
The water signal dominates the 1H MR spectrum in most organs and – if not properly suppressed – will introduce baseline artifacts and sideband signals that are difficult to separate from the small metabolite signals. This led to its bad reputation. However, we will argue in favor of the indicted water signal by demonstrating multiple favorable uses of the water signal – in particular, if not suppressed by presaturation. In the second half, recent use cases from our group will be shown with benefits from using metabolite cycling for parametric mapping from multi-echo trains and diffusion-weighted spectroscopy of the prostate.
Rudy Rizzo
Postdoc University & Inselspital Bern
Rudy is a young engineer whose background spans signal processing, data modeling and analysis, and machine learning. He has freshly defended his Ph.D. at the MRM group (Kreis lab) in Bern, Switzerland, exploring research on MR physics tailored to the acquisition, processing, and quantification of multiparametric MR Spectroscopy (MRS) data and applications of Deep Learning in the MRS field. Soon, he will join the MIITT group in Ann Arbor, Michigan, as a postdoc in the Seiberlich lab to explore new horizons in low-field MR, integrating and optimizing new methodologies for abdomen MRI.
His research projects are focusing on
- Multi-parametric single voxel spectroscopy and spectroscopic imaging for simultaneous fast and accurate quantification of brain and prostate metabolite concentrations and T2s
- Theoretical assessments of robustness and reliability of Deep Learning approaches to quantify metabolites in MR spectroscopy.
- Diffusion-Weighted Spectroscopy in the prostate: comparing healthy and prostate cancer metabolite diffusivity.
Date and time
Friday, July 7th from 10h00 to 11h00 CEST
Location
Virtual on Zoom and on-site CIBM Seminar Room, EPFL Campus, 1015 Lausanne.
Please register by Thursday 6th, 2023
To join us on Zoom, please register here
To attend on-site, please register here, as places are limited.
After registering, you will receive a confirmation email containing information about joining the meeting.
We look forward to seeing you there!
Visitors’ Talk Chair
Cristina Cudalbu
CIBM MRI EPFL Animal Imaging & Technology Section