CIBM participated in the global flagship conference on Magnetic Resonance Imaging of the International Society for Magnetic Resonance in Medicine (ISMRM), held 8-14 August. Although this edition of ISMRM 2020 was virtual, there was a strong presence by members of the CIBM Community.

The CIBM staff together with CIBM affiliate and associate members presented work resulting from their fruitful collaborations through pre-recorded video presentations, Live Q/A Sessions, as well as digital posters.

Participant Professor Paul Thomson from the Imaging Genetics Center (IGC) at the University of Southern California, United States praised the Session on Deep Q-Space Imaging to measure brain cell size, density and diameters, presented by Ileana Jelescu, Research Staff Scientist and 14T MRI Operational Manager, CIBM MRI EPFL, calling it “Mind-blowing”.

A few words from CIBM core members:

“I am proud to announce that CIBM affiliate member Dr. Christopher Roy is among the 2020 recipients of the prestigious Junior Fellow Awards. Furthermore, two abstracts were selected to be presented at the Awards session in the respective Group meetings:

  • Simone Rumac (PhD student supervised by Dr. Ruud van Heeswijk) in the ISMRM Cardiac Study Group Meeting
  • Mariana Falcão (under the mentorship of Dr. Christopher Roy) in the ISMRM Flow and Motion Study Group Meeting.

The final results are currently outstanding. “

Prof. Matthias Stuber, Section Head, CIBM MRI CHUV-UNIL

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“The organizers did an overall fantastic job at switching such a large conference to a virtual format in a very short timeframe. The quality of the talks was excellent, possibly an advantage of pre-recordings. I still missed the direct interaction of in-person meetings and the potential for extended discussions, but we should also embrace the benefits of virtual meetings: reduced cost and carbon footprint, as well as easier to reconcile with other daily duties, be they work or family related.”

Dr. Ileana Jelescu, Research Staff Scientist and 14T MRI Operational Manager, CIBM MRI EPFL

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“I highly appreciated the possibility to have face-to-face discussions with colleagues all over the world through the Networking Lounge. I, like others, missed the direct discussions, the work lunches and the dinners with colleagues/friends. The pre-recorded talks and teaching sessions on MRS were excellent with several talks on denoising… There was indeed a very short time to convert a meeting with + 5,000 accepted abstracts in a virtual meeting, and the organizers worked hard for that. We even had the possibility to discuss with the exhibitors.”

Dr. Cristina Ramona Cudalbu, Research Staff Scientist and 9.4T MRI Operational Manager, CIBM MRI EPFL

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The following non-exhaustive list of 40 papers depict the wide range of topics and diverse research areas covered by the members of the CIBM community at ISMRM 2020.  We may have unknowingly missed one, please drop us a line at mediacom@cibm.ch  and we will be happy to add it here. 

Session: Neurodegeneration 1

Sub-Topic: Dementia

summa-ribbon“Spatio-temporal alterations in functional connectivity, microstructure and cerebral glucose metabolism in a rat model of sporadic Alzheimer’s”

Yujian Diao1, Catarina Tristão Pereira2, Carole Poitry-Yamate1, Ting Yin1, Analina Raquel da Silva1, Rolf Gruetter1, and Ileana Ozana Jelescu1
(1Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 2Faculdade de Ciências da Universidade de Lisboa, Lisbon, Portugal)

Session: Machine Learning and Tissue Characterisation in CMR

Sub-Topic: CMR Tissue Characterisation

summa-ribbon“Cardiac MR fingerprinting with a short acquisition window in healthy volunteers and 62 consecutive patients referred for clinical CMR”

Simone Rumac1, Anna Giulia Pavon2, Jesse Hamilton3, David Rodrigues1, Nicole Seiberlich3, Juerg Schwitter2, and Ruud B. van Heeswijk1
(1Department of Radiology, Lausanne University Hospital (CHUV), Lausanne, Switzerland, 2Cardiology Service, Lausanne University Hospital (CHUV), Lausanne, Switzerland, 3Department of Radiology, University of Michigan, Ann Arbor, MI, United States)

Session: CEST, MT, Zero-TE and Relaxometry

Sub-Topic: Contrast Mechanisms: Acquisition & Fitting Methods

summa-ribbon“Fat fraction mapping using bSSFP Signal Profile Asymmetries for Robust multi-Compartment Quantification (SPARCQ)”

Giulia MC Rossi1,2, Tom Hilbert1,2,3, Adèle LC Mackowiak1,2, Katarzyna Pierzchała4,5, Tobias Kober1,2,3, and Jessica AM Bastiaansen1
(1Department of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 2Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, 3LTS5, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 4Laboratory for Functional and Metabolic Imaging, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 5Center for Biomedical Imaging (CIBM), Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland)

Session: Cardiovascular Techniques

Sub-Topic: MRA & Atherosclerosis Imaging

summa-ribbon“Motion Compensated Coronary MRA using Focused Navigation (fNAV)”
Christopher W. Roy1, John Heerfordt1,2, Davide Piccini1,2, Juerg Schwitter3, and Matthias Stuber1,4
(1Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, 2Advanced Clinical Imaging Technology (ACIT), Siemens Healthcare AG, Lausanne, Switzerland, 3Division of Cardiology and CMR-Center, Lausanne University Hospital (CHUV), Lausanne, Switzerland, 4Center for Biomedical Imaging (CIBM), Lausanne, Switzerland)

Session: Pediatric Neuro

Sub-Topic: Fetal/Newborn/Developmental

magna-ribbon“The neonatal preterm brain: A connectome analysis”
Joana S. de Almeida1, Djalel-Eddine Meskaldji1,2, Serafeim Loukas1,3, Lara Lordier1, Laura Gui4, François Lazeyras4, and Petra S. Hüppi1

(1Department of Women-Children-Teenagers, Hôpitaux Universitaires de Genève, Genève, Switzerland, 2Institute of Mathematics, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 3Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 4Department of Radiology and Medical Informatics, CIBM, University of Geneva, Genève, Switzerland)

Session: Hyperpolarized MR

Sub-Topic: Hyperpolarized 13C Metabolic Imaging for Clinical Research

magna-ribbon“Metabolism of the hyperpolarized neuroprotective agents [1-13C] lactate and [1-13C] pyruvate in a mouse model of transient ischemic stroke”
Thanh Phong Lê1,2, Lara Buscemi3, Elise Vinckenbosch1, Mario Lepore4, Lorenz Hirt4, Jean-Noël Hyacinthe1,5, and Mor Mishkovsky2

(1Geneva School of Health Sciences, HES-SO University of Applied Sciences and Arts Western Switzerland, Geneva, Switzerland, 2Laboratory of Functional and Metabolic Imaging, École polytechnique fédérale de Lausanne (EPFL), Lausanne, Switzerland, 3Department of Clinical Neurosciences, Lausanne University Hospital (CHUV), Lausanne, Switzerland, 4Center for Biomedical Imaging – Animal Imaging and Technology (CIBM-AIT), École polytechnique fédérale de Lausanne (EPFL), Lausanne, Switzerland, 5Image Guided Intervention Laboratory, University of Geneva (UNIGE), Geneva, Switzerland)

Session: MRS and Molecular Imaging, Development and Applications

Sub-Topic: Molecular Imaging Technical Developments & Novel Applications

magna-ribbon“Cerebral metabolism of hyperpolarized [2H7, U-13C6]D-glucose in the healthy mouse under different anesthetic conditions”
Emmanuelle Flatt1, Bernard Lanz1, Andrea Capozzi1, Magnus Karlsson2, Mathilde H.Lerche2, Rolf Grütter1,3, and Mor Mishkovsky1

(1LIFMET, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 2Danmarks Tekniske Universitet, Lyngby, Denmark, 3CIBM, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland)

Session: Multiple Sclerosis & Myelin

Sub-Topic: Multiple Sclerosis: From Structure to Function

magna-ribbon“A quantification of myelin and axonal damage across multiple sclerosis lesions and clinical subtypes with myelin and diffusion MRI”
Reza Rahmanzadeh1,2, Po-Jui Lu1,2, Muhamed Barakovic1,2, Riccardo Galbusera1,2, Matthias Weigel1,2,3, Pietro Maggi4, Thanh D. Nguyen5, Simona Schiavi6, Francesco La Rosa 7,8, Daniel S. Reich9, Pascal Sati9, Yi Wang5, Meritxell Bach-Cuadra7,8, Ernst-Wilhelm Radue1, Jens Kuhle2, Ludwig Kappos2, and Cristina Granziera1,2

(1Translational Imaging in Neurology (ThINk) Basel, Department of Medicine and Biomedical Engineering, University Hospital Basel and University of Basel, Basel, Switzerland, 2Neurologic Clinic and Policlinic, Departments of Medicine, Clinical Research and Biomedical Engineering, University Hospital Basel and University of Basel, Basel, Switzerland, 3Radiological Physics, Department of Radiology, University Hospital Basel, Basel, Switzerland, 4Department of Neurology, Lausanne University Hospital, Lausanne, Switzerland, 5Department of Radiology, Weill Cornell Medical College, New York, NY, United States, 6Department of Computer Science, University of Verona, Verona, Italy, 7Signal Processing Laboratory (LTSS), Ecole polytechnique fédérale de Lausanne (EPFL), Lausanne, Switzerland, 8Radiology Department, Center for Biomedical Imaging, Lausanne University and University Hospital, Lausanne, Switzerland, 9National Institute of Neurological Disorders and Stroke, Translational Neuroradiology Section, Division of Neuroimmunology and Neurovirology, Bethesda, MD, United States)

Sub-Topic: Multiple Sclerosis: QSM, Relaxation & Diffusion Imaging

“Quantitative susceptibility of thalamus, basal ganglia and normal appearing white matter in multiple sclerosis”

Gibran Manasseh1, Mário João Fartaria2,3,4, Tom Hilbert2, Jérémy Deverdun5, Meritxell Bach Cuadra6, Philippe Maeder1, Patric Hagmann1, Tobias Kober2, and Vincent Dunet1
(1Department of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 2Department of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne; Siemens Healthcare AG; École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 3Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, 4Signal Processing Laboratory (LTS 5), École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 5I2FH, Institut d’Imagerie Fonctionnelle Humaine, Montpellier University Hospital Center, Gui de Chauliac Hospital, Montpellier, France, 6Department of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne; École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland)

Session: Cardiovascular Techniques

Sub-Topic: CMR: Machine Learning & AI

“Learning cardiac morphology from MR images using a generative adversarial network: a proof of concept study”

Davide Piccini1,2,3, Aurélien Maillot1,2, John Heerfordt1,2, Dimitri Van De Ville4,5, Juerg Schwitter6, Matthias Stuber2,7, Jonas Richiardi1,2, and Tobias Kober1,2,3
(1Advanced Clinical Imaging Technology, Siemens Healthcare, Lausanne, Switzerland, 2Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 3LTS5, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 4Institute of Bioengineering/Center for Neuroprosthetics, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 5Department of Radiology and Medical Informatics, University Hospital of Geneva (HUG), Geneva, Switzerland, 6Division of Cardiology and Cardiac MR Center, University Hospital of Lausanne (CHUV), Lausanne, Switzerland, 7Center for Biomedical Imaging (CIBM), Lausanne, Switzerland)

Sub-Topic: CMR: Emerging Techniques

“Stabilized decompositions for improved cardiac self-gating: A proof-of-concept in single breath-hold 3D cine imaging”

Anna Padée1, Lorenzo Di Sopra2, John Heerfordt2,3, Jérôme Yerly2,4, Marco Merlo1, Tobias Kober2,3,5, Davide Piccini2,3,5, Matthias Stuber2,4, Christopher Roy2, and Jonas Richiardi2,3
(1Laboratory for Psychiatric Neuroscience and Psychotherapy, University of Fribourg, Fribourg, Switzerland, 2Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 3Advanced Clinical Imaging Technology, Siemens Healthcare, Lausanne, Switzerland, 4Center for Biomedical Imaging, Lausanne, Switzerland, 5LTS5, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland)

Sub-Topic: Cardiovascular MRI Techniques & Applications 1

“Cardiac self-gating signals for free-running imaging: more than just triggers?”

Lorenzo Di Sopra1, Jérôme Yerly1,2, Christopher W. Roy1, Juerg Schwitter3, and Matthias Stuber1,2
(1Department of Diagnostic and Interventional Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, 2Center for Biomedical Imaging (CIBM), Lausanne, Switzerland, 3Division of Cardiology and Cardiac MR Center, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland)

Sub-Topic: 4D Flow & Even Higher

“5D Flow – A quantitative in vivo comparison between Self-Gating and Pilot Tone Gating”

Mariana B. L. Falcão1, Lorenzo Di Sopra1, Liliana Ma2,3, Mario Bacher1,4, Davide Piccini1,5, Jérôme Yerly11,6, Peter Speier4, Tobias Rutz7, Milan Prša7, Michael Markl2,3, Matthias Stuber1,6, and Christopher Roy1
(1Department of Diagnostic and Interventional Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, 2Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, 3Department of Biomedical Engineering, Northwestern University, Chicago, IL, United States, 4Siemens Healthcare GmbH, Erlangen, Germany, 5Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, 6Center for Biomedical Imaging, Lausanne, Switzerland, 7Department of Cardiology, Lausanne University Hospital (CHUV), Lausanne, Switzerland)

Sub-Topic: Coronary & Thoracic MR Angiography

“Similarity-Based Angiography (SIMBA) for Fast Reconstruction of Static Whole-Heart Coronary MR Images from Free-Running Acquisitions”

John Heerfordt1,2, Kevin K. Whitehead3, Jessica A.M. Bastiaansen1, Lorenzo Di Sopra1, Christopher W. Roy1, Jérôme Yerly1,4, Mark A. Fogel3, Matthias Stuber1,4, and Davide Piccini1,2
(1Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 2Advanced Clinical Imaging Technology, Siemens Healthcare, Lausanne, Switzerland, 3Children’s Hospital of Philadelphia, Philadelphia, PA, United States, 4Center for Biomedical Imaging (CIBM), Lausanne, Switzerland)

Session: Brain-Gut Axis and AI in Neuroimaging

Sub-Topic: AI Applications in Neuroimaging: High Novelty & Impact

“The substantial influence of negative sampling and prevalence when presenting classification results: case study with TOF-MRA”

Tommaso Di Noto1, Guillaume Marie1, Sebastien Tourbier1, Guillaume Saliou1, Meritxell Bach Cuadra1,2,3, Patric Hagmann1, and Jonas Richiardi1,4
(1Faculty of Biology and Medicine, Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, 2Medical Image Analysis Laboratory (MIAL), Centre d’Imagerie BioMédicale (CIBM), Lausanne, Switzerland, 3Signal Processing Laboratory (LTS 5), Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 4Advanced Clinical Imaging Technology, Siemens Healthcare, Lausanne, Switzerland)

Session: Diffusion Microstructure Modeling and Validation

Sub-Topic: Diffusion: Microstructure Modelling

“Water exchange time between gray matter compartments in vivo

Ileana Ozana Jelescu1 and Dmitry S Novikov2
(1Center for Biomedical Imaging, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 2Dept. of Radiology, New York University School of Medicine, New York, NY, United States)

Session: fMRI: Multimodal & Preclinical

Sub-Topic: fMRI Preclinical

“An optimized pipeline for functional network identification in rat brain with resting-state fMRI”

Yujian Diao1, Rolf Gruetter1, and Ileana Ozana Jelescu1
(1Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland)

Session: Mitigating motion, artifacts and imperfections

Sub-Topic: Motion Correction: Brain

“Head motion estimation and correction using slab-selective FIDnavs”

Nurten Ceren Askin Incebacak1, Tess E. Wallace2, Tobias Kober3,4,5, Francois Lazeyras1, Simon K. Warfield2, and Onur Afacan2
(1Department of Radiology and CIBM, University of Geneva, Geneva, Switzerland, 2Department of Radiology, Boston Children’s Hospital and Harvard Medical School, Boston, MA, United States, 3Advanced Clinical Imaging Technology, Siemens Healthcare, Lausanne, Switzerland, 4Department of Radiology, UNIL and CHUV, Laussanne, Switzerland, 5LTS5, EPFL, Lausanne, Switzerland)

Session: MRS: New Developments, Applicatons, & Fighting the Noise

Sub-Topic: MRS Applications

“Diffusion of brain metabolites highlights altered brain microstructure in chronic hepatic encephalopathy”

Cristina Cudalbu1, Katarzyna Pierzchala1,2,3, Dunja Simicic1,2, Graham Knott4, Stephanie Clerc-Rosset4, Bernard Lanz2, and Ileana Jelescu1

(1Centre d’Imagerie Biomedicale, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 2Laboratory for functional and metabolic imaging, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 3Service of Clinical Chemistry, University of Lausanne and University Hospital of Lausanne, Lausanne, Switzerland, 4Biological Electron Microscopy Facility, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland)

Sub-Topic: MRS: Deep Learning & Denoising

“MP-PCA denoising dramatically improves SNR in large-sized MRS data: an illustration in diffusion-weighted MRS”

Ileana Ozana Jelescu1, Jelle Veraart2, and Cristina Cudalbu1

(1Center for Biomedical Imaging, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 2Dept. of Radiology, New York University School of Medicine, New York, NY, United States)

Session: New Techniques in MRS

Sub-Topic: MRS Reconstruction & AI

“31P Magnetic Resonance Spectroscopy analyzed and quantified by Convolutional Neural Network (CNN)”

Julien Songeon1, Sebastien Courvoisier1, Antoine Klauser1, Alban Longchamp2, Jean-Marc Corpataux2, Leo Buhler3, and François Lazeyras1
(1Department of Radiology and Medical Informatics, University of Geneva, Geneva, Switzerland, 2Department of Vascular Surgery, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland, 3Faculty of Science and Medicine, Section of Medicine, University of Fribourg, Fribourg, Switzerland)

Sub-Topic: MRS Technical 3

“Improved GABA editing and macromolecule suppression with adiabatic and highly selective Gaussian pulses at 7T”

Song-I Lim1 and Lijing Xin1
(1Centre d’Imagerie BioMédicale (CIBM), Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland)

“Dual-voxel 1H MR spectroscopy in mouse brain at 14.1T with dynamic shim update (DSU) acquisition scheme”

Hikari Yoshihara1, Nicolas Kunz2, Jean-Claude Martinou3, and Hongxia Lei2
(1Laboratory for Metabolic Imaging, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 2Animal Imaging and Technology Core (AIT), Center for Biomedical Imaging (CIBM), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 3Faculty of Science, University of Geneva, Geneva, Switzerland)

“T2 relaxation times of seven individual macromolecules in rat brain 1H MR Spectra at 9.4T: single inversion recovery and AMARES post processing”

Dunja Simicic1,2, Veronika Rackayova2, and Cristina Cudalbu2
(1LIFMET, EPFL, Lausanne, Switzerland, 2CIBM, EPFL, Lausanne, Switzerland)

Session: Other Nuclei MRI and MRS to Study Metabolism

Sub-Topic: Simultaneous or Interleaved MRS & X-Nuclei

“Multimodal assessment of brain energy metabolism in a rat model of hepatic encephalopathy using 1H-MRS and 18F-FDG PET – a pilot study”

Jessie Mosso1,2, Carole Poitry-Yamate1, Dunja Simicic1,2, Mario Lepore1, Cristina Cudalbu1, and Bernard Lanz2

(1Center for biomedical imaging (CIBM), EPFL, Lausanne, Switzerland, 2Laboratory for functional and metabolic imaging (LIFMET), EPFL, Lausanne, Switzerland)

“Cerebral energy metabolism and neurotransmission in a schizophrenia mouse model: a combined 1H-[13C] MRS and 13C MRS study at 14.1T”

Bernard Lanz1, Radek Skupienski2,3,4, Kim Q Do2, and Lijing Xin3
(1LIFMET, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 2Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital (CHUV), Prilly, Switzerland, 3Center for Biomedical Imaging (CIBM), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 4HES-SO, University of Applied Sciences of Western Switzerland, HEIA-FR, Institute of Chemical Technology, Fribourg, Switzerland)

Session: Pediatric Innovations

Sub-Topic: Pediatric High-End Potpourri

“Neurometabolism in children with chronic liver disease or portosystemic shunting: a 1H-MRS/MRI study at 7T”

Cristina Cudalbu1, Lijing Xin1, Bénédicte Maréchal2,3,4, Tobias Kober2,3,4, Sarah Lachat5, Nathalie Valenza6, Florence Zangas-Gehri6, and Valérie McLin5
(1Centre d’Imagerie Biomedicale, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland, 2Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, 3Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 4LTS5, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 5Swiss Pediatric Liver Center, Department of Pediatrics, Gynecology and Obstetrics, University Hospitals Geneva, and University of Geneva Medical School, Geneva, Switzerland, 6Pediatric Neurology Unit, Department of Pediatrics, Gynecology and Obstetrics, University Hospitals Geneva, and University of Geneva Medical School, Geneva, Switzerland)

Session: Quantitative Tissue Properties and Novel Contrast Mechanisms

Sub-Topic: Novel Contrast & Water/Fat Separation

“Optimized fast fat-fraction mapping in the knee using Signal Profile Asymmetries for Robust multi-Compartment Quantification (SPARCQ)”

Adèle LC Mackowiak1,2,3, Tom Hilbert3,4, Giulia MC Rossi1,3, Tobias Kober3,4, and Jessica AM Bastiaansen1
(1Department of Diagnostic and Interventional Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, 2Department of Physics, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 3Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, 4LTS5, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland)

Session: Cancer Imaging: Perfusion & Permeability

Sub-Topic: Perfusion

“Reproducibility of intravoxel incoherent motion MRI of pancreas tumor and healthy pancreas”

Ting Yin1 , Chao Ma2, Shiyue Chen2, Rolf Gruetter1 , and Jianping Lu2

(1CIBM-AIT, Ecole polytechnique federale de Lausanne, Lausanne, Switzerland, 2Department of Radiology, Changhai Hospital of Shanghai, Shanghai, China )

Session: High field, Head, Neck & Neurogems

Sub-Topic: Treasure Chest of Neurogems 2

“NAD+/NADH dysregulation and brain homeostasis in the gclm-KO mouse: towards biomarker identification for schizophrenia”

Radek Skupienski1,2 , Kim Quang Do1 , and Lijing Xin2

(1Center for psychiatric neurosciences, Lausanne University Hospital (CHUV), Prilly-Lausanne, Switzerland, 2Center for Biomedical Imaging (CIBM), Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland )

Session: Interventional MR

Sub-Topic: MR-Guided HIFU

“Enhancement of the MRgHIFU therapy using endovascular sono-sensitizers demonstrated in an experimental model of perfused tissue”

Orane Lorton1, Ryan Holman1, Pauline Guillemin1, Stéphane Desgranges2, Laura Gui1, Lindsey A. Crowe3, François Lazeyras3, Antonio Nastasi4, Christiane Contino-Pépin2, and Rares Salomir1,3

(1Image Guided Interventions Laboratory,University of Geneva, Faculty of Medicine, Geneva, Switzerland, 2University of Avignon, CBSA-IBMM (UMR5247), Avignon, France, 3Radiology Department, University Hospitals of Geneva,, Geneva, Switzerland, 4Research and Development Laboratory, Visceral and Transplantation Service, University Hospital Geneva, Geneva, Switzerland)

Sub-Topic: MR Thermometry Methods

“Reference-free PRFS thermometry using 3D spherical harmonic functions”

Laura Gui1, Orane Lorton1, Max Scheffler2, and Rares Salomir1,2

(1Image Guided Interventions Laboratory, Faculty of Medicine, University of Geneva, Geneva, Switzerland, 2Department of Radiology, University Hospitals of Geneva, Geneva, Switzerland)

Session: RF coils

Sub-Topic: Dielectric Materials & Metamaterials for Coils

“Dielectric Resonators and Dipole Antennas Combined: New Approach in Radio Frequency Coil Design for Ultrahigh Field MRI”

Daniel Wenz1 and Rolf Gruetter1,2,3,4

(1Center for Biomedical Imaging – Animal Imaging and Technology (CIBM-AIT), Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 2Laboratory of Functional and Metabolic Imaging (LIFMET), Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 3Department of Radiology, University of Lausanne, Lausanne, Switzerland, 4Department of Radiology, University of Geneva, Geneva, Switzerland)

“Dielectrically-Shortened Dipole Antennas for MRI at 7.0 T: Thick or Thin?”

Daniel Wenz1 and Rolf Gruetter1,2,3,4

(1Center for Biomedical Imaging – Animal Imaging and Technology (CIBM-AIT), Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 2Laboratory of Functional and Metabolic Imaging (LIFMET), Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 3Department of Radiology, University of Lausanne, Lausanne, Switzerland, 4Department of Radiology, University of Geneva, Geneva, Switzerland)

“Saddle Coil Design for MRI/MRS at 14.1 Tesla: A Favorable Alternative to the Quadrature Birdcage Coil”

Claudia Christina Zanella1, Jérémie Daniel Clément1,2, Daniel Wenz3, Bernard Lanz1, and Rolf Gruetter11

(1Laboratory for Functional and Metabolic Imaging (LIFMET), EPFL, Lausanne, Switzerland, 2School of Biomedical Engineering and Imaging, King’s College London, London, United Kingdom, 3Center for Biomedical Imaging – Animal and Imaging Technology (CIBM-AIT), EPFL, Lausanne, Switzerland)

Session: Cancer Imaging: Pre- & Post-Treatment

Sub-Topic: Cancer Imaging: Physiology & Metabolism

“Hyperpolarized 13C-glucose MRS: a potential biosensor to visualize the infiltrative front in GBM”

Mor Mishkovsky1, Olga Gusyatiner2, Bernard Lanz1, Cristina Cudalbu3, Irene Vassallo2, Marie-France Hamou2, Jocelyne Bloch2, Arnaud Comment4, Rolf Gruetter1,3,5,6, and Monika Hegi2

(1Laboratory for Functional and Metabolic Imaging (LIFMET), Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 2Department of Clinical Neurosciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 3Centre d’Imagerie Biomédicale (CIBM), Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 4General Electric Healthcare, Chalfont St Giles, United Kingdom, 5Department of Radiology, University of Geneva (UNIGE), Geneva, Switzerland, 6Department of Radiology, University of Lausanne (UNIL), Lausanne, Switzerland)

Session: Cancer Imaging: Preclinical & Miscellaneous

Sub-Topic: Preclinical: Models & Methods

“Comparison of metabolic fluxes in the mouse dorsal hippocampus and hypothalamus using indirect 1H-[13C] MRS upon [1,6-13C2] glucose infusion”

Antoine Cherix1, Bernard Lanz1, and Hongxia Lei2

(1Laboratory for Functional and Metabolic, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 2Animal Imaging and Technology Core (AIT), Center for Biomedical Imaging (CIBM), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland)

Session: Hyperpolarization and Molecular Imaging

Sub-Topic: Hyperpolarization 2

“Radical-free and metal-free hyperpolarized MRI using endogenous pyruvate analogues”

Claudia C Zanella1, Andrea Capozzi1, Hikari A I Yoshihara1, Alice Radaelli1, Lionel P Arn2,3, Rolf Gruetter1, and Jessica A M Bastiaansen2,3
(1Laboratory for Functional and Metabolic Imaging (LIFMET), EPFL, Lausanne, Switzerland, 2Department of Diagnostic and Interventional Radiology, CHUV, Lausanne, Switzerland, 3Department of Diagnostic and Interventional Radiology, UNIL, Lausanne, Switzerland)

Session: Hyperpolarized MR

Sub-Topic: New Frontiers in Hyperpolarization

“Detection of renal PEP-CK activity with hyperpolarized 13C-aspartate”

Hikari A. I. Yoshihara1 and Juerg Schwitter2,3
(1Laboratory for Functional and Metabolic Imaging, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland, 2Division of Cardiology, Lausanne University Hospital (CHUV), Lausanne, Switzerland, 3Cardiac MR Center, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland)

Session: Neuroimaging and AI

Sub-Topic: Neuroimaging & AI: Applications from Stroke to MS

“Automatic detection of Multiple Sclerosis cortical lesions based on 3D-FLAIR and MP2RAGE sequences”

Francesco La Rosa1,2, Ahmed Abdulkadir3, Mário João Fartaria1,2,4, Reza Rahmanzadeh5,6, Riccardo Galbusera5,6, Jean-Philippe Thiran1,2, Cristina Granziera5,6, and Meritxell Bach Cuadra1,2
(1LTS5, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 2Radiology Department, Center for Biomedical Imaging, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 3Universitäre Psychiatrische Dienste and University of Bern, Bern, Switzerland, 4Siemens Healthcare AG Switzerland, Lausanne, Switzerland, 5Neurologic Clinic and Policlinic, Departments of Medicine, Clinical Research and Biomedical Engineering, University Hospital Basel and University of Basel, Basel, Switzerland, 6Translational Imaging in Neurology (ThINk) Basel, Department of Medicine and Biomedical Engineering, University Hospital Basel and University of Basel, Basel, Switzerland)

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