AUTHORS: Wang CH, Hua TE, Chien CC, Yu YL, Yang TY, Liu CJ, Leng,WH, Hwu Y, Yang YC, Kim CC, Je JH, Chen CH, Lin HM, Margaritondo G

Materials Chemistry and Physics, 106(2-3): 323-329, December 2007

ABSTRACT

Reductant, stabilizer-free colloidal gold solutions were fabricated by a new room-temperature synchrotron X-ray irradiation method. The influence of process parameters such as the pH value and the exposure time on the structure of gold nanoparticles was investigated. The mechanisms underlying the X-ray-triggered reduction of gold ions and the formation of gold clusters are discussed in detail. The X-ray irradiation derived highly concentrated gold nanoparticles are readily to be re-dispersed and possess suitable colloidal stability within cellular environment. The characterization included a study of the possible cytotoxicity for the EMT-6 tumor cell line: the negative results indicate that the gold clusters produced with our approach are biocompatible.

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