Landmark Detection for Fusion of Fundus and MRI Towards a Patient-Specific Multi-Modal Eye Model
AUTHORS: De Zanet SI, Ciller C, Rudolph T, Maeder P, Munier F, Balmer A, Bach Cuadra M, Kowal JH
IEEE Transactions on Biomedical Engineering, 62(2): 532-40, February 2015
Ophthalmologists typically acquire different image modalities to diagnose eye pathologies. They comprise, e.g., Fundus photography, optical coherence tomography, computed tomography, and magnetic resonance imaging (MRI). Yet, these images are often complementary and do express the same pathologies in a different way. Some pathologies are only visible in a particular modality. Thus, it is beneficial for the ophthalmologist to have these modalities fused into a single patient-specific model. The goal of this paper is a fusion of Fundus photography with segmented MRI volumes. This adds information to MRI that was not visible before like vessels and the macula. This paper contributions include automatic detection of the optic disc, the fovea, the optic axis, and an automatic segmentation of the vitreous humor of the eye.