On Thursday December 12th, Dr. Pascal Sati – Staff Scientist in the Translational Neuroradiology Section of the National Institute of Neurological Disorders and Stroke in Bethesda, Maryland – discussed innovative magnetic resonance imaging for the diagnosis of multiple sclerosis at the CIBM.
Multiple sclerosis (MS) is a complex disease, and its clinical and radiologic heterogeneity often make its diagnosis challenging and may result in misdiagnosis. Therefore, there is a crucial need for a highly specific and sensitive biomarker for MS. The central vein sign (CVS) has recently been proposed as a novel imaging biomarker to improve the accuracy and speed of MS diagnosis.
During this talk, Dr. Sati first introduced the concept of CVS in MS and its discovery using 7-tesla MRI. Then, he presented innovative MRI techniques developed at 3-tesla for enabling the investigation of the CVS in a clinical setting, and provided an update of the evidence from recent single-center and multi-center clinical studies on the diagnostic value of the CVS. Finally, Dr. Pascal Sati discussed ongoing technological developments aimed at integrating the CVS in the clinical practice.