AUTHORS: Wang Z., Alemán Gómez Y., Cleusix M., Jenni R., Alameda L., Conus P., Bach Cuadra M., Hagmann P., Do K. Q., Xin L.

ISMRM, : , Toronto, Canada, June 2023


ABSTRACT

This study aims to investigate brain cortex alterations in early psychosis patients (n = 42) compared to healthy control subjects (n=35). Surface-based morphometric analysis using MP2RAGE images at 7T revealed significant clusters (corrected p<0.05) where the cortical area and cortex volume in early psychosis patients are reduced compared to healthy controls at the junction of lateral occipital, lingual and peri calcarine region at left hemisphere after permutation multiple comparison correction. Bilateral cortical areas, thickness, and volumes of the patients were reported to be changed at the surface vertex level.


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