Breakfast & Science Seminar 5

We are pleased to invite you to the fifth of the regular CIBM Breakfast & Science Seminar series for 2020 (every last Tuesday of the month) and due to COVID-19 continues to take place through video conference only:

Date: Tuesday May 26th, 2020

Program:

• 9:00-9:30: “The MRI scanner as a sharp in vivo microscope: from white to gray matter “, by Ileana Jelescu, Research Staff Scientist, CIBM MRI EPFL Animal Imaging & Technology Section

  • Abstract: Can we obtain sub-millimeter information about tissue structure in vivo and non-invasively? In a diffusion MRI experiment, the signal encodes information about length scales of a few microns – much smaller than the actual MR image resolution of millimeters – and thus about features of the underlying tissue microstructure that lie in the mesoscale and that we otherwise cannot spatially resolve in vivo. The main challenge of the field is to decode this information and output specific and reliable biophysical parameters of tissue microstructure. In this talk, I will summarize the long and winding road to establishing a reliable biophysical model for diffusion in white matter and illustrate its tremendous potential in a few applications. I will then present our first steps into the next challenge for our field: developing reliable model(s) for cortical and deep gray matter.

• 9:30-10:00: “GlobalBioIm — Imaging as an inverse problem made easy” by Pol del Aguila Pla, Research Staff Scientist, CIBM SP EPFL Mathematical Imaging Section

  • Abstract: Most image reconstruction methods across biomedical imaging rely on the successful formalism of imaging as an inverse problem. In this framework, an imaging system is represented as a transformation of a continuous quantity (e.g., a density of fluorophores over a certain plane or volume) into a number of measurements. Image reconstruction is then understood as the recovery of the original continuous quantity. The successful design of reconstruction methods following this paradigm involves both advanced mathematics to reliably incorporate prior knowledge and major efforts to develop efficient algorithms. In this talk, I explain the basic concepts of the field and show how our library “GlobalBioIm” can facilitate your research, with a couple of running examples to showcase its different functionalities.

• 10:00-10:30 : Short introduction by audience members and Interactive sharing session

Please register by Monday May 25, 2020, 12:00 at the following link: https://epfl.zoom.us/meeting/register/v5YsdOGqqzIt2JvJC30eZwAOkGDtlkn3hQ .

After registering, you will receive a confirmation email containing information about joining the meeting.

We look forward to seeing you again soon.